A mild and efficient method for the selective deprotection of silyl ethers using KF in the presence of tetraethylene glycol.

نویسندگان

  • Hailong Yan
  • Joong-Suk Oh
  • Choong Eui Song
چکیده

A mild and efficient protocol for the deprotection of silyl ethers using KF in tetraethylene glycol is reported. A wide range of alcoholic silyl ethers can be selectively cleaved in high yield in the presence of certain acid- and base-labile functional groups. Moreover, the phenolic silyl ethers were cleaved exclusively, without affecting the alcoholic silyl ethers, at room temperature.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 9 23  شماره 

صفحات  -

تاریخ انتشار 2011